Re: [pronut-hiv] Request for information on macro and micronutrientsupplements for people living with HIV/AIDS (3)

["Rachel Stern" <sternworks@verizon.net>]

is the B6 a typo?


----- "George M. Carter" wrote:
>
>   It's  always  rather appalled me that the researchers who have studied
>   nutrition  and  multivitamins, with a few exceptions, have been unable
>   to   make   proper  recommendations  for  something  as  simple  as  a
>   multivitamin/mineral  tablet for people living with HIV. We know there
>   are  documented  deficiencies of a ranger of micronutrients, including
>   minerals  such  as  magnesium  (Skurnick),  selenium (various), sulfur
>   (Droge)  and  others.  Calcium appears to be important as well. And of
>   course,  among the various vitamins (A, the Bs, C, E). By contrast, it
>   may make sense to use an iron-free multi, only supplementing with iron
>   where an iron-deficiency anemia has been documented, if that is deemed
>   feasible and reasonable.
>   The  protocol used by Jon Kaiser that showed an increase of 25% in CD4
>   counts  also  included  antioxidants,  including the primary source of
>   sulfur deficiency, N-acetylcysteine. I've appended that formula below.
>   Note  that the primary outcome of offsetting ARV-associated peripheral
>   neuropathy  was  not  achieved  in their study. However, Youle et al.,
>   using  acetylcarnitine  alone  at  a  higher  dose  of 3 g/day did see
>   improvement in PN.
>   While  it appears unlikely that the antioxidants would be included due
>   to cost considerations, an interesting alternative might be the use of
>   whey  proteins which help offset the loss of glutamine and cysteine in
>   HIV-infected   individuals   and   may   represent   a  cost-effective
>   supplement.  In  addition,  I would think a potent multi/mineral combo
>   would  not  be  unduly  costly, have no side effects and could help to
>   slow  or  delay progression, as well as reduce morbidity and mortality
>   (the Tanzanian and Thai studies).
>   I  hope  that  the  Indian government will see the virtue and value of
>   making  these types of interventions available. On the community side,
>   I  think  one  of  the  other  challenges  will  be  helping people to
>   understand  the  use  of  these medications and encouraging their use.
>   Pill  count  can be a problem. And we all realize how very little many
>   people  in  India eat at all; one meal consisting of dal and rice on a
>   good day. How about Horlix?
>   George M. Carter
>   **
>   Kaiser protocol:
>   Table 1. Broad-Spectrum Micronutrient Formula (Total Daily Dosage)
>   Multivitamin Multimineral
>   Vitamin A 8,000 i.u.
>   Beta Carotene 20,000 i.u.
>   Vitamin C 1,800 mg
>   Vitamin D 400 i.u.
>   Vitamin E 800 i.u.
>   Vitamin B1 60 mg
>   Vitamin B2 60 mg
>   Vitamin B6 260 mg
>   Niacinamide 60 mg
>   Folic acid 800 mcg
>   Vitamin B12 2.5 mg
>   Pantothenic acid 60 mg
>   Biotin 50 mcg
>   Choline 60 mg
>   Inositol 60 mg
>   Glutamic acid 100 mg
>   Betaine HCL 150 mg
>   Bioflavinoid complex 300 mg
>   Calcium 800 mg
>   Iron 18 mg
>   Iodine 150 mcg
>   Magnesium 400 mg
>   Zinc 30 mg
>   Selenium 200 mcg
>   Copper 2.0 mg
>   Manganese 10 mg
>   Chromium 100 mcg
>   Molybdenum 300 mcg
>   Boron 2.0 mg
>   Potassium 99 mg
>   Highly Potent Antioxidants
>   Alpha lipoic Acid 400 mg
>   N-acetyl cysteine (NAC) 1200 mg
>   Acetyl L-carnitine 1000 mg