[pronut-hiv] Studies Disagree On Safety of Lemon Juice Against HIV

["ProNut-HIV" <pronut-hiv@healthnet.org>]

SciDev.Net (London)
Catherine Brahic

Potentially contradictory findings on whether lemon and lime juice
could safely protect women from HIV infection if they apply it to their
vaginas will be presented at an international conference later this
month.

Researchers from the CONRAD programme at the Eastern Virginia Medical
School, United States are expected to present evidence that lemon or
lime juice can damage the cells of the vagina.

Another US-based team, from the University of Berkeley, will suggest
however that lime juice is safe if it is used in low concentrations.

Historical documents show that through the centuries, women have used
acidic solutions such as vinegar as a contraceptive.

But in the past few decades, research has suggested that the acidic
juice of lemons and limes could also function as a microbicide -- a
product that women apply to their vaginas to protect themselves from HIV
infection.

Studies show that this practice is already common among sex workers in
Nigeria, and anecdotal evidence suggests it also takes place in other
African countries.

But the safety and efficacy of using lime juice has not yet been proven
scientifically, and some researchers are concerned that women could
begin using lemon and lime juice with potentially harmful effects.

In February, Carol Lackman-Smith of the Southern Research Institute,
United States, presented data at a conference showing that 50 per cent
solutions of the juices damaged the cells that line the vagina.

The CONRAD team is expected to confirm the finding at this month's
Microbicides 2006 conference in Cape Town, South Africa.

According to the team's preliminary results, most women who applied
pure or 50 per cent dilutions of lime juice to their vaginas later
showed signs of damage to the vaginal tissues.

Lackerman-Smith says there are grounds to be concerned about the safety
of using lime or lemon juice.

However, Anke Hemmerling of the University of Berkeley will present
results in Cape Town that suggest that weaker dilutions of 10-20 per
cent cause little, if any, damage to the lining of the vagina.
 
Hemmerling says the difference could be because it is difficult to
assess the extent of vaginal damage.

The prospect of using lemon or lime juice as a microbicide is also
complicated by the fact that sperm reduces the overall acidity inside
the vagina.